[1-(1,1-dimethylpropyl)-1H-indol-3-yl]-2-naphthalenyl-methanone
\nJWH 018 is a synthetic cannabinoid (CB) that potently activates the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors (Ki = 9.0 and 2.94 nM, respectively).{16797} This cannabimimetic compound has frequently been found in herbal blends. {18620,18621,18618} JWH 018 2’-naphthyl-N-(1,1-dimethylpropyl) isomer differs from JWH 018 structurally by having a 1,1-dimethylpropyl chain, rather than a pentyl chain, extending from the indole group and the naphthyl moiety attached at its 2 position. The biological activities of this compound have not been characterized. This product is intended for forensic purposes.
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