1-naphthalenyl(1-pentyl-1H-pyrrol-3-yl)-methanone
\n JWH 030 is a naphthoyl pyrrole cannabimimetic which activates the CB1 receptor (EC50 = 30.5 nM for rat, Ki = 87 nM for mouse) better than CB2 (EC50 = 552 nM for human CB2).{11496,20068} JWH 030 is quite potent in vivo in the mouse spontaneous activity and tail flick (antinociception) assays (ED50 = 26.8 μM/kg).{20068} It also dose-dependently inhibits electrically-induced contractions of the mouse vas deferens (IC50 = 3.38 nM).{20069} This product is intended for forensic or research purposes.
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