4,9-dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole
\n Harmaline is a psychoactive indole found naturally in certain plants. Its stimulating activities are achieved, in part, through inhibition of monoamine oxidases, thus increasing the levels of monoamine neurotransmitters (e.g., at 7-70 μM/kg in rats).{20018} Harmaline (30 mg/kg) induces tremor in mice through the N-methyl-D-aspartate (NMDA) receptor, at which harmaline may act as an inverse agonist.{20017,20019} This compound has also been identified as an adulterant in herbal mixtures containing synthetic cannabinoids and described as contributing to poisoning when combined with a hallucinogenic tryptamine.{19506,20016} This product is intended for forensic or research purposes.
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