[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]-1-naphthalenyl-methanone
\n JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor ligand. It binds to the CB1 receptor with high-affinity (IC50 = 7.8-42 nM).{16961,16684} The effects of JWH 200 in locomotor activity, tail-flick latency, hypothermia and ring-immobility tests are comparable or superior to Δ9-THC or WIN 55,212.{16963} It potently inhibits the contraction of electrically-stimulated murine vas deferens (IC50 = 3.7-6.0 nM).{16960,16962}
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