2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine, monohydrochloride
\n 2C-NBOMe (Item No. 9001096) is an analytical reference standard that is structurally categorized as a phenethylamine. 25C-NBOMe is a derivative of 2C-C having an N-(2-methoxybenzyl) addition at the amine. 2C-C is a known hallucinogen that stimulates monoamine receptor activity and inhibits the re-uptake of serotonin and norepinephrine in rat brain synaptosomes (IC50 = 31 and 63 μM, respectively).{19271,19758} The N-(2-methoxybenzyl) addition to 2C-NBOMe increases the affinity and selectivity for the 5-HT2A receptor over other serotonin receptors.{20442} Radiolabeled 25C-NBOMe has been used for positron emission tomography imaging of the 5-HT2A receptor in porcine brain.{21331} This product is intended for forensic and research uses.
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