(1s,3s)-adamantan-1-yl(1-pentyl-1H-indol-3-yl)methanone
\n JWH 018 adamantyl analog is a mildly selective agonist of the peripheral cannabinoid receptor, where the naphthalene ring is substituted with an adamantyl group.{18291} Adamantyl substitutions provide structural rigidity and bulk. Though no biological activity has been reported for JWH 018 adamantyl analog, Δ8-THC analogs with adamantyl substituted for the carbon side chain demonstrate improved affinity and selectivity of central cannabinoid and peripheral cannabinoid receptor binding.{13958} This synthetic cannabinoid has been identified in a herbal product.{20992}
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