Explore the Cutting-Edge Amsphere™ Protein A Chromatography Resins
Join Our Exclusive Beta Program for Amsphere™ A+ and Amsphere™ A3 Protein A Chromatography Resins
4 June, 2024 by
Andrew Heath

Join Amsphere A+ Beta Program

Introduction to JSR Corporation

JSR Corporation is a global leader in innovative materials, dedicated to advancing life sciences. Our expertise and commitment to excellence drive us to develop groundbreaking solutions for the biopharmaceutical industry.

Overview of Amsphere™ Protein A ResinsAmsphere A3 Brochure

Our Amsphere™ line of Protein A resins is designed for superior affinity purification, ensuring high yield and purity in antibody production. These resins are essential in the downstream process of antibody drug production.

Features of Amsphere™ A3

Amsphere™ A3 is the next generation protein A affinity resin with outstanding performance features:

  • High Dynamic Binding Capacity (DBC): Maximizes antibody capture, reducing process time and increasing yield.
  • Superior Caustic Stability: Maintains performance even under rigorous cleaning conditions, capable of withstanding up to 300 cycles with 0.1 M NaOH.
  • Impurity Clearance: Achieves industry-standard impurity clearance, ensuring low levels of HCP, DNA, and aggregates.

Amsphere™ A3 is already in use for GMP manufacturing in clinical and commercial stages, demonstrating its robustness and reliability in various applications, including Fc-fusion molecules and antibody fragments​​. Download the brochure here.

Amsphere A+ Brochure

Introducing the New Amsphere™ A+

Amsphere™ A+ is the latest addition to our Amsphere™ product line, offering several enhancements:

  • Improved DBC and Pressure Properties: Features a newly designed Protein A ligand and base matrix, providing better performance.
  • Alkali Stability: Demonstrates significantly improved stability with a novel Protein A ligand, making it suitable for extended use.
  • Affinity for Non-Classical mAbs: Shows strong affinity for non-classical mAbs such as Fc fusion and bispecific antibodies.

Amsphere™ A+ maintains stable DBC and recovery yield performance while minimizing HCP and Protein A leach throughout its lifecycle​​. Download the brochure here.

Invitation to the Beta Program

We are excited to invite you to participate in our exclusive beta program for Amsphere™ A+. This program offers you the opportunity to:

  • Evaluate New Technology: Be among the first to test and benefit from our latest advancements in Protein A chromatography resins.
  • Provide Feedback: Share your insights and experiences to help us further enhance our products.
  • Optimize Your Processes: Gain access to cutting-edge resins that can improve your antibody purification processes.